Selected Publications

1. Santana-Blank L, Rodríguez-Santana E. Photobiomodulation in Light of Our Biological Clock’s Inner Workings. Photomed Laser Surg. 2018; 36(3):119-121.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863078/
2. Santana-Blank L. Rodríguez-Santana E, Santana-Rodríguez KE, Reyes-Barrios H. “Quantum leap” in photobiomodulation therapy ushers in a new generation of light-based treatments for cancer and other complex diseases. Photomed Laser Surg. 2016; 34(3):1-12.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782038/
3. Santana-Blank L, Rodríguez-Santana E, Santana-Rodríguez K.E., Santana-Rodríguez J.A., and Reyes H. “Water’s Many Roles in Laser Photobiomodulation.” Journal of Cancer Research and Treatment, 2015;3(1): 1-5. doi:10.12691/jcrt-3-1-1.
https://www.researchgate.net/publication/294428588_Water’s_Many_Roles_in_Laser_Photobiomodulation
4. Santana-Blank L, Rodríguez-Santana E, Santana-Rodríguez K.E., Santana-Rodríguez J.A., and Reyes H. “Water as a photoacceptor, energy transducer and selective rechargeable electrolytic biobattery in photobiomodulation for cancer and other complex diseases.” The 27th Annual and International Meeting of The Japanese Association for Animal Cell Technology. JAACT 2014 . Kitakyushu International Conference Center, “Bioscience on Water and Life” Symposium. Kitakyushu, Japan. 11- 14 November. Wide-spread cell engineering world. Program & Abstracts S4-3:25-26.
https://www.researchgate.net/publication/294428723_Water_as_a_photoacceptor_energy_transducer_and_selective_rechargeable_electrolytic_biobattery_in_photobiomodulation_for_cancer_and_other_complex_diseases
5. Heberto Reyes, Elizabeth Rodríguez-Santana, Jesús A. Santana-Rodríguez, Karin E. Santana- Rodríguez, and Luis Santana-Blank, “Decoding the Ice-Water Energy Paradox in the DW-MRI Phantom for Tumors: Targeting Thermodynamics, Kinetic and Structural Molecular Mechanisms Commentary.” Journal of Cancer Research and Treatment.2014; 2 (1):19-21.
https://www.researchgate.net/publication/293814313_Decoding_the_Ice-Water_Energy_Paradox_in_the_DW-MRI_Phantom_for_Tumors_Targeting_Thermodynamics_Kinetic_and_Structural_Molecular_Mechanisms_Commentary
6. Rodríguez-Santana E., and Santana-Blank L. Emerging evidence on the crystalline water-light interface relating to ophthalmology and therapeutic implications in photobiomodulation. First communication. Photomedicine & Laser Surgery. 2014; 32(4): 240-242.
https://www.researchgate.net/publication/260397638_Emerging_Evidence_on_the_Crystalline_Water-light_Interface_in_Ophthalmology_and_Therapeutic_Implications_in_Photobiomodulation_First_Communication
7. Conference proceeding. Santana-Blank L, Rodríguez-Santana E, Reyes H, Santana-Rodríguez J, Santana-Rodríguez K. Water-light interaction: A novel pathway for multi hallmark therapy in cancer. Int J Cancer Ther Oncol 2014; 2(1):02012. DOI: 10.14319/ijcto.0201.2
https://www.researchgate.net/publication/293814935_Water-light_interaction_A_novel_pathway_for_multi_hallmark_therapy_in_cancer
8. Santana-Blank L, Rodríguez-Santana E, Reyes H, Santana-Rodríguez J A, Santana-Rodríguez KE. Water-light interaction: A novel pathway for multi hallmark therapy in cancer. Int J Cancer Ther Oncol 2013; 2(1):0201.2. DOI: 10.14319/ijcto.0201.2
https://www.researchgate.net/publication/293814935_Water-light_interaction_A_novel_pathway_for_multi_hallmark_therapy_in_cancer
9. Santana-Blank L, Rodríguez-Santana E, Reye H, Santana-Rodriguez JA, Santana-Rodríguez KE. Abstract. Water-light interaction: A novel pathway for multi hallmark therapy in cancer. The 8th Annual Conference on the Physics, Chemistry and Biology of Water. October 22-25, 2013. Borovets, Bulgaria. 
http://www.waterconf.org/participants-materials/abstracts/Luis%20Santana-Blank%20%20Abstract%20Santana-Blank.pdf
10. Santana-Blank L, Rodríguez-Santana E, Reye H, Santana-Rodriguez JA, Santana-Rodríguez KE. Laser photobiomodulation: A new promising player for the multi-hallmark treatment of advanced cancer. International Journal of Cancer Therapy and Oncology (IJCTO) 2013; 1(1):01012. DOI: 10.14319/ijcto.0101.2
https://www.researchgate.net/publication/293816053_Laser_photobiomodulation_A_new_promising_player_for_the_multi-hallmark_treatment_of_advanced_cancer
11. Santana-Blank L, Rodríguez-Santana E, Santana-Rodríguez JA, Santana-Rodríguez KE. Photobiomodulation of Aqueous Interfaces: Finding Evidence to Support the Exclusion Zone in Experimental and Clinical Studies. Photomedicine & Laser Surgery. 2013; 31(9):461-462. 
https://pubmed.ncbi.nlm.nih.gov/24047224/
12. Rodríguez-Santana E., Santana-Blank L. Laser Photobiomodulation as a Potential Multi-Hallmark Therapy for Age-Related Macular Degeneration. Guest Editorial. Photomed Laser Surg. 2013; 31(9):409-410. 
https://www.researchgate.net/publication/243965121_Laser_Photobiomodulation_as_a_Potential_Multi-Hallmark_Therapy_for_Age-Related_Macular_Degeneration
13. Santana-Blank L, Rodríguez-Santana E, Santana-Rodríguez JA, Santana-Rodríguez KE, Reyes H. Laser photobiomodulation as a potential multi-target anticancer therapy-review. Journal of Solid Tumors. 2013;3(2):50-62.
https://www.researchgate.net/publication/276225750_Laser_Photobiomodulation_as_a_Potential_Multi-Target_Anticancer_Therapy-Review 
14. Santana Blank L, Rodríguez-Santana E, Santana-Rodriguez JA, Santana-Rodríguez KE. Solid Tumors and Photobiomodulation: A Novel Approach to Induce Physiologically Reparative Homeostasis / Homeokinesis Journal of Solid Tumors. 2012; 2(6):23-35.
https://www.researchgate.net/publication/273692021_Solid_Tumors_and_Photobiomodulation_A_Novel_Approach_to_Induce_Physiologically_Reparative_Homeostasis_Homeokinesis_Review
15. Santana Blank L, Rodríguez-Santana E, and Santana-Rodríguez KE. Letter to the Editor: Concurrence of Emerging Developments in Photobiomodulation and Cancer. Photomedicine & Laser Surgery. 2012; 30:615-6 
https://www.liebertpub.com/doi/abs/10.1089/pho.2012.3374
16. Luis Santana-Blank, Elizabeth Rodríguez-Santana,Karin E. Santana-Rodríguez. Photobiomodulation of Aqueous Interface as Selective Rechargeable Bio-Batteries in Complex Diseases. Photomed Laser Surg.2012; 30(5):242-9 
https://pubmed.ncbi.nlm.nih.gov/22429016/
17. Luis Santana-Blank,Elizabeth Rodríguez-Santana,Karin E.Santana-Rodríguez. Cancer, Warburg Effect and Laser Photobiomodulation – Progress Beyond Skepticism. Journal of Chinese Clinical Medicine 2011; 6 (3):147-157.
https://www.researchgate.net/publication/276225750_Laser_Photobiomodulation_as_a_Potential_Multi-Target_Anticancer_Therapy-Review
18. Elizabeth Rodríguez-Santana, Luis A. Santana-Blank, Karin E. Santana-Rodríguez. Hypotensor Effect of Photo-Infrared Pulsed Biomodulation over Intraocular Pressure. Journal of Chinese Clinical Medicine 2011; 6 (4):147-157.
http://www.fundalas.org/publications/IOP%20Manuscript%20el%209-9-2011.pdf
19. Santana-Blank L, Rodríguez-Santana E. The interaction of light with nanoscopic layers of water may be essential to the future of photobiomodulation. Photomed Laser Surg. 2010 Aug; 28 Suppl 1:S173-4. 
https://www.liebertpub.com/doi/10.1089/pho.2009.2745
20. Santana-Blank L, Rodríguez-Santana E, Santana-Rodríguez K. Theoretic, experimental, clinical bases of the water oscillator hypothesis in near-infrared photobiomodulation. Photomed Laser Surg. 2010 Aug; 28 Suppl 1:S41-52. Review.
https://www.researchgate.net/publication/45280505_Theoretic_Experimental_Clinical_Bases_of_the_Water_Oscillator_Hypothesis_in_Near-Infrared_Photobiomodulation
21. Elizabeth Rodriguez-Santana, Magally Belisario, Luis Santana-Blank. Hypotensor therapeutic effect over intraocular pressure with laser photo-biomodulation. Novel mechanistic proposal.” (Report of Interventional Cases Serie). Proceeding S.V.O. (LVII National Congress of Ophthalmology.
Binational Colombian-Venezuelan Congress of Cataract and Refractive Surgery. Binational Congress of Strabismus and Pediatric Ophthalmology. Porlamar, Island of Margarita, Nueva Esparta). Glaucoma-Poster No.29 Page 96, 2009. 
http://fundalas.org/publications.html
22. E. Rodriguez-Santana, H. Reyes, KE Santana-Rodriguez, L. Santana-Blank. Photo-infrared pulsed biomodulation in age-related macular degeneration associated to neurological disease: one interventional case report and mini-review. Journal of Chinese Clinical Medicine 2008; 3 (8): 470- 477. 
https://www.researchgate.net/publication/294090972_Photo-infrared_pulsed_biomodulation_in_agerelated_macular_degeneration_associated_to_neurological_disease_one_interventional_case_report_and_mini-review
23. E. Rodriguez-Santana, H. Reyes, L. Santana-Blank. Photo-Infrared Pulsed Biomodulation in Age-Related Macular Degeneration Associated to Neurological Disease” (Interventional Case Report.). Proceeding SVO (LVI Venezuelan National Congress of Ophthalmology). Retina- Poster N° 78 Page 115, 2008. 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768515/
24. Santana-Blank LA, Rodríguez-Santana E. Physiologic rhythms responding to low-level electromagnetic and mechanical signals: the Joule equivalence principle. Photomed Laser Surg. 2008 Aug; 26(4):405-6.
https://www.researchgate.net/publication/51420854_Physiologic_Rhythms_Responding_to_Low-Level_Electromagnetic_and_Mechanical_Signals_The_Joule_Equivalence_Principle
25. Santana-Blank LA, Rodríguez-Santana E, Santana-Rodríguez KE. Photo-infrared pulsed bio-modulation (PIPBM): a novel mechanism for the enhancement of physiologically reparative responses. Photomed Laser Surg. 2005 Aug;23(4):416-24. Review. 
https://pubmed.ncbi.nlm.nih.gov/16144487/
26. Santana-Blank L. Effects of an infrared pulsed laser device (IPLD) over apoptosis in cancer cells. Bioelectromagnetics. 2005 Sep;26 (6):523-4.
https://www.researchgate.net/publication/7652705_Effects_of_an_infrared_pulsed_laser_device_I PLD_over_apoptosis_in_cancer_cells
27. Santana-Blank LA, Reyes H, Rodríguez-Santana E, Santana-Rodríguez KE Microdensitometry of T2-weighted magnetic resonance (MR) images from patients with advanced neoplasias in a phase I clinical trial of an infrared pulsed laser device (IPLD).Lasers Surg Med. 2004; 34 (5):398-406.
https://pubmed.ncbi.nlm.nih.gov/15216533/
28. Santana-Blank L. Exchanging ideas about research that is both methodologically sound and scientifically relevant.Photomed Laser Surg. 2004 Oct;22(5):442-3.
https://pubmed.ncbi.nlm.nih.gov/15682511/
29. Santana-Blank L. Contraindications in noninvasive laser therapy: truth and fiction. Photomed Laser Surg. 2004 Oct; 22(5):442; author reply 442.
https://www.liebertpub.com/doi/10.1089/pho.2004.22.442
30. Rodríguez-Santana E, Santana-Blank LA, Reyes H, Santana-Rodríguez KE, Hunger M, Orellana R, Ortega D. H-NMR spin-lattice and correlation times of burned soft-tissue after treatment with an infrared pulsed laser device. Lasers Surg Med. 2003;33(3):190-8.
https://www.researchgate.net/publication/5309827_H-NMR_spin-lattice_and_correlation_times_of_burned_soft-tissue_after_treatment_with_an_infrared_pulsed_laser_device
31. Santana-Blank L. Modulated low-energy near-infrared (NIR) lasers and cancer: an invitation to discuss a new treatment approach. Lasers Surg Med. 2003;32(1):1-2.
https://onlinelibrary.wiley.com/doi/abs/10.1002/lsm.10143
32. Santana-Blank LA, Rodríguez-Santana E, Vargas F, Santana-Rodríguez KE. Photo-induced cytomorphologic changes in an advanced cancer phase I clinical trial. Lasers Surg Med. 2002;30(1):18-25. 
https://onlinelibrary.wiley.com/doi/abs/10.1002/lsm.10017
33. Santana-Blank LA, Rodríguez-Santana E, Vargas F, Reyes H, Fernández-Andrade P, Rukos S, et al. Phase I trial of an infrared pulsed laser device in patients with advanced neoplasias. Clin Cancer Res. 2002; 8: 3082-3091. 
https://clincancerres.aacrjournals.org/content/8/10/3082
34. Luis A. Santana-Blank, Elizabeth Rodríguez-Santana, Daniel Scott-Algara, Manfred Hunger, Karin E. Santana-Rodríguez, Rafael Orellana. Short-Term Bioeffects of an Infrared Pulsed Laser Device on Burned Rat Skin Monitored by Transverse Relaxation Times (NMR). Lasers in Surgery and Medicine 2000. 27:411- 419. 
https://onlinelibrary.wiley.com/doi/abs/10.1002/1096-9101(2000)27:5%3C411::AID-LSM1002%3E3.0.CO%3B2-P
35. Santana-Blank, L. A., Castes, M., Rojas, M. E., Vargas, F., and Scott-Algara, D. Evaluation of serum levels of tumor necrosis factor-(TNF-a) and soluble IL-2 receptor (sIL-2R) and CD4. CD8 and natural killer (NK) populations during infrared pulsed laser device (IPLD) treatment. Clin. Exp. Immunol., 90:0 43–48, 1992. 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1554554/
Book chapter – Luis Santana-Blank, Elizabeth Rodríguez-Santana, Jesus A. Santana-Rodríguez, Karin E. Santana- Rodríguez, Heberto Reyes. Water as a photoacceptor, energy transducer and rechargeable electrolytic biobattery in photobiomodulation. IN: “Handbook of Low Level Laser (Light)Therapy”.
Chapter N°8 . Editors: Michael Hamblin, Tanupriya Agrawal and Marcelo de Sousa, to be published by Pan Stanford Publishing Pte. June 30, 2016
http://www.pthomegroup.com/sites/default/files/my%20liberary/Michael%20R%20Hamblin%20Marcelo%20Victor%20Pires%20de%20Sousa%20Tanupriya%20AgrawalHandbook%20of%20Low%20Level%20Laser%20Therapy%20Pan%20Stanford%202017.pdf